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diagnosis management cardiology differential hematology table clinical disease infectiousdiseases syndrome medications causes microbiology oncology adultonset algorithm antibiotics covid19 indications overview
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... Systemic AOSD: high fever ... #AdultOnset #Stills ... Disease #AOSD #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... #AdultOnset #Stills ... diagnosis #management #treatment ... #rheumatology
CMV vs EBV - Mononucleosis Acute CMV Infection: • Asymptomatic (most common) • Infectious mononucleosis (fever/chills, malaise)
mononucleosis (fever ... /chills, malaise ... ) • Fever: More ... common EBV • Fever ... Mononucleosis #diagnosis #comparison
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... AOSD #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Treatment: • Corticosteroids
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... : No • Treatment ... #diagnosis #comparison
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... production • Treatment ... BrighamChiefs #Fever ... #Hyperthermia #comparison
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... infection • Still's ... • Rheumatic fever ... SLE, Rheumatic fever ... • New murmur, fever
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... Inflammation: high fever ... , malaise, chills ... TREATMENT: ​• Acute ... gabrieltalledop #Oroya #Fever
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... criteria: - Fever ... with concomitant fever ... #AdultOnset #Stills ... #Major #Minor #Rheumatology
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