24 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... #AdultOnset #Stills ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : High spiking fever ... Systemic AOSD: high fever ... #rheumatology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... infection • Still's ... • Rheumatic fever ... SLE, Rheumatic fever ... • New murmur, fever
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #diagnosis #rheumatology
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Non-Infectious: • Rheumatologic ... Mediterranean Fever ... : EGPA, Horton Disease ... , Takayasu Disease ... Diagnosis #Causes #cardiology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
treat infectious diseases ... Pneumonia - Typhoid fever ... respiratory distress syndrome ... InfectiousDiseases #Infections #Pharmacology ... #Management #Treatment
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
the population Disease ... Insect stings Disease ... symptoms - Headache, fever ... Urticaria #diagnosis #rheumatology ... #comparison #table
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... +, Adult-onset Still ... disease, Infection ... #summary #rheumatology
Causes of Myocarditis 
1. Infectious Myocarditis
 • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
Coxiella bumetti (Q fever ... Mountain Spotted fever ... virus, yellow fever ... Junin virus, Lassa fever ... (rheumatic fever