25 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Disease Acute ... crisis: • Fever ... Supportive with treatment ... hepatomegaly and anemia ... cholestasis: • Fever
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Treatment: • Consider ... stem cell transplant ... if neutropenic fever ... diagnosis #management #treatment ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- Pel-Ebstein fever ... the spleen or liver ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
- Cr >2 mg/dL or ... 40 ml/min A - Anemia ... diseases, CML, ... MGUS #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
) B symptoms → fevers ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... bartonella (oroya fever ... ARUPLabs #Hemolytic #Anemia ... Algorithm #workup #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
explain symptoms • Fever ... fluid balance, and CXR ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
symptoms - Headache, fever ... histology - Mast cell ... doi: 10.1111/all ... Urticaria #diagnosis #rheumatology ... #comparison #table