23 results
diagnosis management comparison arthritis differential hemeonc hemophagocytic hlh leukemia lymphohistiocytosis chronic hodgkins lymphocytic lymphoma summary syndrome testing algorithm anemia apml
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... manifestations, hypoxia, CXR ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... the spleen or liver ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... cells can indicate disease ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... disease (diverse ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... fluid balance, and CXR ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
symptoms - Headache, fever ... histology - Mast cell ... doi: 10.1111/all ... Urticaria #diagnosis #rheumatology ... #comparison #table
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Subacute-Acute: • Common: fever ... diagnosis #management #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
) B symptoms → fevers ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... syndrome): - Hematologic ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... • Autoimmune diseases ... Unknown cause Treatment ... #summary #rheumatology
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