18 results
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
30mm length) • Fever ... Criteria: • Abdominal ... distention • Abdominal ... Diagnosis #criteria #hematology ... #oncology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... ) General: Fever ... valve lesions Abdominal ... Thrombocytopenia #Lupus #SLE ... symptoms #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Constitutional domain: Fever ... pericarditis • Hematologic ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Diagnosis #Management #Hematology ... #Rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- Pel-Ebstein fever ... translocation • Types: Classification ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Autoimmune diseases: SLE ... Unknown cause Treatment ... #summary #rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... CT abdomen if abdominal ... or HSCT - CRS: fever ... therapy - Symptoms: fever
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Skin Disease Classification ... Non-autoimmune rheumatologic ... to: Arthritis, Fever ... Erythematosus #Diagnosis #Rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... diagnosis #management #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis