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Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Brucellosis, Q fever ... Malignancy: - Hematologic ... Mediterranean fever ... , Factitious fever
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Rickettsial diseases ... • Crohn disease ... Non-Infectious Causes ... #Differential #Diagnosis
Faget Sign - Pulse-Temperature Dissociation Causes of Relative Bradycardia • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... , Drug fever ... #differential #diagnosis
Faget's Sign & Liebermeister's Rule Pulse-Temperature Dissociation EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM INFECTIOUS
• Typhoid Fever ... • Drug Fever ... CLINICAL UTILITY ... Typhoid Fever (S ... #Dissociation #diagnosis
Causes of Relative Bradycardia - Note the propensity for intracellular organisms. Infectious: Legionella, Psittacosis, Q fever, Typhoid
Causes of Relative ... , Typhoid fever, ... , Dengue fever, ... #bradycardia #Causes ... #differential #diagnosis
Differential Diagnosis - Noninfectious Causes of Fever CRITICAL DIAGNOSES: - Acute myocardial infarction - Pulmonary embolism or
Noninfectious Causes ... of Fever CRITICAL ... - Sickle cell disease ... - Drug fever ... Postmyocardiotomy syndrome #Fever
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... hepatic crisis: • Fever ... cholestasis: • Fever ... Hepatobiliary #hepatology ... #differential #diagnosis
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Causes of Fever ... Other: • Drug fever ... • Factitious fever ... • Rheumatic fever ... parasites #Fever
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
Onset Still's Disease ... criteria: - Fever ... with concomitant fever ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
pharyngeal erythema, fever ... pharyngeal erythema, fever ... attack meninges -> Fever ... Sudden onset of fever ... pruritic rash, fever
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