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diagnosis hepatitis differential alcoholic gastroenterology aclf aki autoimmune chronic cirrhosis drug druginduced failure hbv hepatitisb hepbv idiosyncratic indications induced kidney
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Injury (DILI) ... or symptoms of liver ... Drug #induced #Liver ... gastroenterology #algorithm
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Failure ( ... months without treatment ... disease, liver ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Alcohol-related liver ... dechallenge • Acute ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... Liver Injury: ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... injury, though ... #Hepatology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Algorithm 1. ... survival in severe AH ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Insufficiency, Liver ... Medications, Spinal Cord Injury ... Differential #Diagnosis #criticalcare ... #algorithm #treatment ... #management
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
infection with severe liver ... injury (INR > 2 ... liver failure ... #Indications #management ... #hepatology
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... • AIN → Consider ... #treatment #management
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Algorithm Assess ... : - Acute kidney ... injury with serum ... HCV, DILI, HCC, ... #Algorithm #hepatology
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