48 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... liver failure ... Liver transplant ... Hepatobiliary #hepatology ... #differential #diagnosis
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... Physical Exam Acute ... LeserTrelat #Sign #PhysicalExam ... #clinical #video ... #dermatology #oncology
Cirrhosis leading to Chronic Liver Failure - Clinical Signs and Symptoms

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings
leading to Chronic Liver ... Failure - Clinical ... Signs #Symptoms #PhysicalExam ... #Findings #Diagnosis ... #Hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... months without treatment ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... Renal Failure Treatment ... #management #hematology ... #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... if neutropenic fever ... progress to MDS or acute ... #management #treatment ... #hematology
Flapping tremors of Asterixis

DDx
- Decompensated cirrhosis or acute liver failure.
- Renal failure /azotemia.
- Respiratory failure with
Decompensated cirrhosis or acute ... liver failure ... hyperammonemia #PhysicalExam ... #clinical #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... ) Differential Diagnosis ... Maternal Support - Critical ... #Pregnancy #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology