10 results
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Homeostasis In the liver ... The gout drug pegloticase ... #Homeostasis #Gout ... #Pathophysiology ... #Pharmacology #
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... inotropy) ACCP Cardiology ... #Classification ... #Classes #pathophysiology ... #phases #cardiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... Vaughan #Williams #Pharmacology ... #Classification ... #Classes #pathophysiology ... #cardiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
developmental level ... Impulsivity • Blurts out ... BehavioralDisorder #Pathophysiology ... signs #psychiatry #criteria
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
• Caused by liver ... exclusion: always rule out ... TIPS West Haven Criteria ... Encephalopathy #Grading #Classification
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... back pain at/near level ... Diagnostic Criteria ... defined sensory level ... • Must rule out
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... irritation, rash, fever ... #Allopurinol #Pharmacology ... #pathophysiology ... #gout #uricacid
Fasciola hepatica - Liver Fluke Life Cycle - Fascioliasis 
Ruminants are the typical definitive hosts.
1) Unembroynated
Fasciola hepatica - Liver ... from eggs, seek out ... migrate though liver ... LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
night sweats, fever ... → TEE • Duke Criteria ... Differential #Diagnosis #cardiology ... #infectiousdiseases
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
developmental level ... >18 years old, criteria ... period • Stays out ... BehavioralDisorder #Pathophysiology ... signs #psychiatry #criteria