10 results
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... (HCPS): Febrile ... • Prodrome: fever ... • Autopsy PCR Treatment ... #microbiology #infectiousdiseases
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
Rash - Diagnostic Algorithm ... angiomatosis, Sweet syndrome ... #Rash #Febrile ... #Diagnosis #Algorithm ... #Schema #InfectiousDiseases
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... Low calcium • Treatment ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... acute or subacute febrile ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Rare: DAH, acute febrile ... Renal Failure Treatment ... Differentiation #Syndrome
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Criteria for Sweet Syndrome ... (Acute Febrile ... Fever, temperature ... Excellent response to treatment ... #Acute #Febrile
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... vasculitis: 10%-16% Liver ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... #Rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... hyperinflammatory syndrome ... search for and treatment ... Treatment Approach ... Diagnosis #Management #Hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... algorithm 2018. ... risk of organ toxicity ... #algorithm #hematology