35 results
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
Therapy ILE is a treatment ... for severe toxicity ... life-threatening toxicity ... #ILE #Therapy #Toxicology ... #Management #Pharmacology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... Glucose, Salicylate level ... Toxic Salicylate Level ... #Toxicology #diagnosis ... #management #Treatment
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... metabolized in the liver ... #Toxicity #Diagnosis ... #Pharmacology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Prodrome: fever ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #infectiousdiseases
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology # ... rheumatology
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug Level ... at anytime if toxicity ... Sample trough level ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Rheumatology