43 results
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... Febrile illness + ARDS ... • Prodrome: fever ... +/- diarrhea Diagnosis ... #microbiology #infectiousdiseases
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
other cause of ARDS ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
AIDS-defining illnesses
 - Candidiasis of the esophagus, bronchi, trachea, or lungs [(but NOT the mouth (thrush)]
AIDS-defining illnesses ... brain - Wasting syndrome ... due to HIV #AIDS ... Illnesses #HIV #InfectiousDiseases ... #Diagnosis #List
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
Streptococcal Toxic Shock Syndrome ... 50% in nec fasc Diagnostic ... (2+): kidneys, liver ... , lung/ARDS, coagulopathy ... #STSS #treatment
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... chills, anorexia, ARDS ... Nodular → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... #diagnosis #management
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Elevated bile acids ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... #differential #diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... anti-synthetase syndrome ... /full triad at diagnosis ... after 2 years of treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... • Bicytopenia Treatment ... #management #treatment ... #hematology