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hematology diagnosis management comparison actions adrenoceptor apml carcinoma causes chemotherapy coagulation cyp3a4 dic differentiation disseminated doac gastroenterology hcc hepatocellular inducers
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... : No • Treatment ... diagnosis #comparison #table
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline First Line Treatment for HCC with Preserved
First Line Treatment ... with Preserved Liver ... #Management #Hepatology ... Gastroenterology #oncology ... #Pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... #oncology
Adrenoceptor Actions α1 • Vascular smooth muscle - Contraction • Genitourinary smooth muscle - Contraction • Intestinal
excitability • Liver ... #Adrenoceptor #adrenergic ... receptors #actions #pharmacology ... #pathophysiology ... #comparison #table
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