13 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... #LiverInjury #Hepatology ... #Pharmacology # ... Causes #DILI
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Diagnosis Algorithm DILI ... non-essential drug/HDS treatments ... for alternative causes ... Diagnosis #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... , vomiting, abdominal ... 10x ULN), ↑Tbili/Dbili ... Antithrombin Ill • Ultrasound ... #Pregnancy #hepatology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
gas on hepatic ultrasound ... ileus), intra-abdominal ... variety of other causes ... portal #venousgas #ultrasound ... #hepatology #liver
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Kidney stones caused ... Postoperative abdominal ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Imaging Modalities for Renal Calculus

AXR. KUB
 - Good far calcium-containing stones useful when limited radiation dose
radiation dose Ultrasound ... obstruction - Able ... of flank or abdominal ... diverticulae). degree and level ... for non-calculus causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Muscle swelling - Fever ... Tachycardia - N/V - Abdominal ... per day until stable ... Diagnosis #Management #causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
, abdominal discomfort ... Dosing: 15 g (4 level ... hypokalemia); nausea ... #medications #pharmacology ... #table #comparison
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Eligibility for Treatment ... >20) - Obtain abdominal ... exclude other causes ... HCV, DILI, HCC, ... Management #Algorithm #hepatology