30 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
injury, often from vascular ... Loss of pain and ... Extremity Dysfunction (pain ... of iniury, pain ... signs #symptoms #msk
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain ... Differential Diagnosis Algorithm ... Marfan's Syndrome ... #JointPain #MSK ... Differential #Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... is the main clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint Pain ... Differential Diagnosis Algorithm ... Sicca) Syndrome ... Inflammatory #JointPain #MSK ... Differential #Diagnosis #Algorithm
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Insufficiency, Liver ... Abdominal compartment syndrome ... , Vascular compression ... #criticalcare #algorithm ... #treatment #management
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
syndrome • Arthritis ... Tarsal tunnel syndrome ... /swelling - Fever ... lower #extremity #msk ... #physicalexam
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Internal derangement/Avascular ... - Autoimmune Rheumatologic ... • Rheumatic fever ... Differential #Diagnosis #MSK ... #rheumatology #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Cathepsin G release → vascular ... effusions, weight gain ... Renal Failure Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Bicytopenia Treatment ... agent are the main ... diagnosis #management #treatment ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
pain/Night sweats ... Osteoarthritis - Overuse syndrome ... Seronegative Reactive Syndrome ... differential #diagnosis #msk ... #physicalexam