150 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology ... diagnosis #management #algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... effect following treatment ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... staphylococcal scalded skin syndrome ... and toxic shock syndrome ... #Diagnosis #Dermatology ... Erythematous #Rash #Algorithm
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... diagnosis #management #hematology
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... sounds, RUQ pain • Dermatologic ... : Tachycardia, Fever ... #Symptoms #spectrum ... #signs #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiency • Liver ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... megaloblastic anemia Treatment ... if neutropenic fever ... #hematology
Genital Skin Ulcers - Differential Diagnosis Algorithm
Painful:
 • Herpes simplex
 • Haemophilus ducreyi (chancroid)
 • Behcet's
Differential Diagnosis Algorithm ... ) • Behcet's syndrome ... ulcerative #skinrash #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Workup • CNS symptoms ... Returning Traveler’ algorithm ... thin smear • Signs ... values supporting hematologic