6905 results
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... #Pharmacology #Diagnosis
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity - Diagnosis ... Glucose, Salicylate level ... Toxic Salicylate Level ... Toxicity #Toxicology #diagnosis ... #management #Treatment
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... /full triad at diagnosis ... after 2 years of treatment ... Autoimmune #Myositis #diagnosis
Summary of Heart Blocks
1st Degree Heart Block:
 • Prolonged PR >200ms (5 small squares).
 • Narrow
• No Treatment ... No Treatment. ... 3:1 block) • Treatment ... Block infranodal level ... degrees #summary #Diagnosis
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... : • 80% have fever ... decubitus - air fluid level ... hemorrhage • Treatment ... several months of treatment
Vitamin D Deficiency - Classification and Treatment - Insufficiency vs Deficiency
Vitamin D Insufficiency:
 • 25(OH)D Level
Classification and Treatment ... Insufficiency: • 25(OH)D Level ... 50 nmol/L) • Treatment ... Deficiency: • 25(OH)D Level ... #management #diagnosis
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
for alternate diagnoses ... CBC, vitamin D level ... deficiency for newly diagnosed ... #Exacerbation #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... • Clinical: fever ... , ↓ Fibrinogen level ... Unknown cause Treatment ... #management #treatment
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
flucloxacillin, vigabatrin Diagnosis ... HAGMA; Paracetamol level ... organic acid screen Treatment ... Oxoprolinuria #diagnosis ... #management #treatment
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Ensure leg is at level ... • Diagnosis: ... including DM • Treatment ... #Emergencies #diagnosis ... #management #treatment