46 results
diagnosis differential management oncology algorithm liver causes injury rheumatology disease laboratory testing aflp aplastic ascites chronic comparison dermatology hellp hemophagocytic
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Supportive with treatment ... hepatomegaly and anemia ... liver failure ... Hepatobiliary #hepatology ... #hepatitis #differential
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... spherocytosis, Hemolytic ... Malignant tumors, Acute ... uremic syndrome ... #differential #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , Acute hemolysis ... , deficiency anemia ... Diagnosis #Algorithm #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Injury: • Early acute ... hepatitis • Acute ... elevated serum LDH level ... • Tumor lysis syndrome ... polyangiitis • Behçet's syndrome
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... 2-5x normal - Hemolysis ... #Patterns #Liver ... #Injury #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... bartonella (oroya fever ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... , Acute biliary ... obstruction, HELLP Syndrome ... Diagnosis #Causes #Acute ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... • Gilbert's syndrome ... • Hemolysis ... #differential #Hepatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Treatment: • Consider ... if neutropenic fever ... progress to MDS or acute ... diagnosis #management #treatment ... #hematology
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