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diagnosis management differential hematology algorithm nephrology syndrome clinical disease classification infectiousdiseases dermatology oncology workup hepatology lupus pharmacology table anemia comparison
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
practices that could cause ... : INR/PT, aPTT(liver ... (CVID, WAS), (neurologic ... bypass), LFT (liver ... #Workup #hematology
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Causes of Hypernatremia ... • Decreased level ... ICU patients • Fever ... Hypernatremia #Nephrology ... Diagnosis #Algorithm #Causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiency • Liver ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology #
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
production • Treatment ... rapidly fatal • Causes ... Serotonin syndrome • Treatment ... Identify underlying cause ... Cooling blankets can cause
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Renal Disease, Liver ... Reticulocytosis • Liver ... Diagnosis #Algorithm #Causes ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, ↓ Fibrinogen level ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... elliptocytosis Extrinsic Causes ... : • Liver disease ... Intravascular Causes ... classification #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... Hypoxia, Uremia, Liver ... Diagnosis #Algorithm #Causes ... #neurology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
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