14 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- HIV • Immune ... immunodeficiency virus (HIV ... index < 2 • EPO Level ... aplastic anemia Treatment ... Anemia #oncology #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Pathophysiology: 2 hit ... : 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... Transfusion #Reactions #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... • Steroids: IV ... diagnosis #management #hematology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... lymphadenopathy, • Abdominal ... #AIDS #pulmonary ... differential #diagnosis #infectiousdiseases
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute pulmonary ... Association class IV ... Postoperative abdominal ... distention • Abdominal ... Tolvaptan) • Treatment
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... mucogenicum • HIV ... enzymes, diarrhea, abdominal ... differential #diagnosis #infectiousdiseases
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- GI tract: abdominal ... Coronary arteries - Fever ... Supply gut -> abdominal ... • HBV HCV • ... differential #diagnosis #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... 3) Abdominal, ... Increased protein level ... normal glucose level ... ) #Mycoses #InfectiousDiseases
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
multiplex • GI tract: Abdominal ... gut involvement, abdominal ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
CT abdomen if abdominal ... Aggressive IV fluids ... IV bisphosphonates ... ICANS: altered level ... renal failure, pulmonary