62 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... : 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Insufficiency, Liver ... • Obstructive: Pulmonary ... Dehydration Shock Treatment ... Differential #Diagnosis #criticalcare ... #algorithm #treatment
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
most common) Clinical ... to rnonths • Fever ... , hemoptysis Treatment ... Abscess #Diagnosis #Pulmonary ... #Clinical #CXR
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
syndromes Clinical ... is the main clinical ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... , ↓ Fibrinogen level ... #summary #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... has five major clinical ... Increased protein level ... normal glucose level ... Aspergillosis Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... Renal Failure Treatment
Stress Ulcer Prophylaxis

Stress ulcerations are common in ICU patients and may lead to hemorrhage if not
ulceration or treatment ... hospitalization) • Pathophysiology ... Risk Factors • Clinical ... #Prophylaxis #criticalcare