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diagnosis differential causes cirrhosis hematology indications acidosis aih aki albumin algorithm amiodarone apml autoimmune chemistry chronic classification criticalcare differentiation diuresis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Failure ( ... months without treatment ... disease, liver ... Injury (DILI) ... #Cirrhosis #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... ALF): • Liver ... Hepatocellular Level ... • Gilbert's syndrome ... #differential #Hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
ascites removed • Acute ... kidney injury ( ... • Hepatorenal syndrome ... #Cirrhosis #treatment ... #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
infection with severe liver ... injury (INR > 2 ... liver failure ... #Indications #management ... #hepatology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
pulmonary edema ... heart failure, liver ... heart failure, liver ... heart failure, liver ... heart failure, liver
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Insufficiency, Liver ... Medications, Spinal Cord Injury ... • Obstructive: Pulmonary ... Abdominal compartment syndrome ... #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Muscle swelling - Fever ... per day until stable ... Differential #Diagnosis #Management ... #nephrology
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... • Hepatorenal syndrome ... Treat underlying liver ... #treatment #management
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... injury, though ... #Hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... the setting of liver ... • Underlying liver ... hypertension • Liver ... #treatment #hepatology
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