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diagnosis hematology algorithm intravascular oncology pruritus rash secondary systemic workup anemia arterial atlas basics bleeding bruising coagulation dermatologic dic disorders
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... microangiopathy: Thrombotic thrombocytopenic ... usually IgM) (e.g. primary ... #Causes #differential ... #diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Causes == Primary ... secondary #systemic #generalized ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm Thrombocytopenia ... • Disseminated Intravascular ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Myelogenous Leukemia • Primary ... following EtOH induced thrombocytopenia ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... /Quantity: • Primary ... Causes: - Thrombocytopenia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Platelet Disorders - Differential ... unclear, or if a primary ... Platelet #Disorders #Differential ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Treatment: • Treat primary ... cause • Correct ... Coagulation #diagnosis #causes ... treatment #management #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... reticularis Differential ... Necrotising vasculitis, extravascular ... rash #diagnosis #rheumatology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
BURROW: burrows are linear ... flat macules of extravascular ... lesions or part of a generalized ... #Diagnosis #Dermatology ... #Skin #Primary
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Testosterone - Coumadin skin ... Heparin-induced thrombocytopenia ... pathophysiology #hematology ... #differential #
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