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diagnosis hematology atlas hemolysis morphology oncology rbc agglutinin algorithm bloodcell calculation causes classification cold dehydrogenase disease elevated extravascular hodgkins index
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
hemolytic anemia ... microangiopathy ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #anemia
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... : • Thrombotic ... microangiopathy ... anemia" • HELLP ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Schistocyte: Microangiopathic ... Hemolytic Anemia ... Unstable hemoglobin disorders ... RBC #Morphology #differential
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Retroperitoneal, Uterine • Hemolysis ... : Autoimmune, Microangiopathic ... hemolytic anemia ... Production #Index #hematology ... #anemia #differential
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... Pelger-Huet, Macrocytic anemia ... @AmyChung #Blood ... #Disorders #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... spherocytosis, Hemolytic ... uremic syndrome, Thrombotic ... key #diagnosis #differential ... #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
deficiency of red blood ... - Acquired: Microangiopathic ... hemolytic anemia ... paralyses CNS Disorders ... Cerebral venous thrombosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... Immunoglobulin M (IgM) • Blood ... younger pts) Differential ... sensitize red blood ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... result in severe anemia ... of Peripheral blood ... anemia Indirect ... WBC count and differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... hematopoiesis cell lineages—erythrocytic ... Neutropenia • Platelet Disorders ... syndromes with single-lineage ... count with differential
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