10 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... Summary #diagnosis #rheumatology ... #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Clinical Features: Lungs ... activation and/or medications ... and leukemia • Lung ... #Diagnosis #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... kidneys, liver, lung ... coagulopathy, erythematous ... #STSS #treatment ... #management #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... rash) • Heart, lung ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Injury (AKI) - Management ... • Hepatorenal syndrome ... underlying liver disease ... the underlying disease ... #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
systemic lupus erythematosus ... , Lyme disease, ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
calcification appears as a linear ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... #Rheumatology # ... diagnosis #management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... Non-small-cell lung ... positive patients Treatment ... Dermatomyositis #diagnosis #management ... #rheumatology #