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diagnosis differential pharmacology cardiology comparison hyperlipidemia primarycare table abnormal adverse algorithm antipsychotics atypical causes decisionaid dyslipidemia nephrology pathophysiology profiles psychiatry
Familial Dyslipidemias • Hyperchylomicronemia • Familial hypercholesterolemia • Dysbetalipoproteinemia • Hypertriglyceridemia Sarah Lyon @sarahthelyon #Familial #Dyslipidemias #lipidemia #cardiology
Familial Dyslipidemias ... #Familial #Dyslipidemias ... #lipidemia #cardiology
Atorvastatin. HMG-CoA reductase inhibitor (statin) for dyslipidemia and MI/stroke prevention. 2nd most prescribed drug in the
inhibitor (statin) for dyslipidemia
Adverse Effects of Antipsychotic Medications - Comparison Table First Generation: chlopromazine, haloperidol, fluphenazine Second Generation: aripirazole, asenapine,
Effects: EPS/TD, Dyslipidemia
NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
hypertension, Diabetes, Dyslipidemia
Risk factors for atherosclerosis Modifiable risk factors: - Dyslipidemia (elevated LDL, decreased HDL) - Tobacco smoking -
risk factors: - Dyslipidemia
Health risks of obesity Greatly increased risk (RR >3): - Mortality (BMI >30) - Type 2
bladder disease - Dyslipidaemia
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Contraceptive) #Dyslipidemia
Fibrates - Gemfibrozil and Fenofibrate Mechanism: activates PPAR alpha Lipid Effects: - Decrease TG by 30-50% -
used to treat dyslipidemia
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
risk factors (Dyslipidemia
Characteristics of Common Lipid Disorders Polygenic hypercholesterolemia Atherogenic dyslipidemia • Frequently accompanied by central obesity or diabetes Familial hypercholesterolemia,
hypercholesterolemia Atherogenic dyslipidemia
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