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management differential criticalcare causes toxicity classification lactic pharmacology algorithm lactate nephrology overview syndrome typea typeb anticoagulation aspirin citrate clinical clozapine
Lactic Acidosis Classification - Type A vs Type B Type A Lactic Acidosis: Sepsis, Ischemic bowel, Hemorrhagic
Lactic Acidosis ... bowel, Hemorrhagic shock ... Hypoperfusion, Cardiogenic shock ... : Liver Disease, ... #TypeA #TypeB #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
glucose by the liver ... contribution of liver ... ->treatments include ... mellitus/DKA - Liver ... gluconeogenesis Liver
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Diagnosis Framework ... Insufficiency, Liver ... Treatment Goals ... #Differential #Diagnosis ... criticalcare #algorithm #treatment
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
Salicylate Toxicity - Diagnosis ... anion-gap metabolic acidosis ... Pulmonary edema, Shock ... Aspirin #Toxicity #Toxicology ... #Treatment
Occult Causes of Non-Response to Vasopressors vital disclaimer: the cognitive response to hypotension should not be reaching
hypotension is treatment ... non-responders: - acidosis ... occult bleeding - toxicologic ... - 2nd cause shock ... #Diagnosis #Nonresponse
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Associated Lactic Acidosis ... cycle found in the liver ... anaerobic metabolism Diagnosis ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
50% in nec fasc Diagnostic ... (2+): kidneys, liver ... necrosis STSS Treatment ... Syndrome #STSS #treatment ... #management #diagnosis
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... Renal: metabolic acidosis ... AI, thyroid dz liver ... Classification #diagnosis
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Cardiogenic & Septic Shock ... Clearance: Systemic liver ... Difficult to diagnosis ... #Differential #Diagnosis
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... Renal: metabolic acidosis ... AI, thyroid dz liver ... Classification #diagnosis
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