11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... Differential Diagnosis Neurologic-Centered ... Ig deposition disease ... #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Anemia (AIHA) Treatment ... Steroids - 1-2 mg/kg ... esp if severe disease ... underlying condition • Monoclonal ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... transformation) Treatment ... chemotherapy for low-risk disease ... fludarabine) 3) Monoclonal ... Leukemia #oncology #hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
antibody - Early treatment ... vaccinations Renal disease ... deposition disease ... rituximab (in clinical ... Complications #diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... Arthritis, AS Treatment ... : monoclonal TNF-aIpha ... signs #symptoms #rheumatology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... Relapsing-remitting course +++ Clinical ... Monoclonal gammopathy ... ) • IVIg 2 g/kg ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... and lower jaw Treatment ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... had more severe disease ... positive patients Treatment ... diagnosis #management #rheumatology ... #dermatology