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diagnosis differential nephrology chloride hyponatremia management alkalosis hypokalemia loopdiuretic metabolic nejm nephro resistance treatment urinary associated ckd classes diuretics endocrinology
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Panel A, loop diuretics ... for binding to sodium–potassium–chloride ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
a Mechanism of Diuretic ... high doses of loop ... diuretics are used ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... as no effect on sodium ... Pharmacology #nephrology #conversion ... #loop #thiazide ... #classes
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... or thiazide diuretics ... - Normal/low ... #causes #urinary
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... Differential #Diagnosis #Algorithm ... #causes #potassium
Causes of Hypomagnesemia - Differential Diagnosis Algorithm GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... Urine Mg > 10g • Loop ... Hypomagnesemia #Magnesium #Low ... #Causes #Differential
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm GI Losses - Gastric • Vomiting • NG suction GI
Causes of Metabolic ... Differential Diagnosis Algorithm ... tubular transport • Diuretics ... (loop/thiazide) ... #Causes
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... alkalosis • Normal/low ... pressure: Active diuretic ... the indicated causes
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Causes of Hypernatremia ... water loss, Serum Sodium ... administration • Osmotic diuresis ... mannitol, glucosuria Low ... #Causes
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... : SIADH, Renal Sodium ... can be high or low ... Primary polydipsia), Low
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