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Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
(B) Treatment algorithm ... Total loop diuretic ... intravenous; SGLT2‐I, sodium–glucose ... following a single loop ... #CHF #Algorithm
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... anhydrase inhibitors, loop ... syndrome (mimics loop ... #Causes #differential
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... - Differential ... Diagnosis Algorithm ... Clinicians should also look ... Post-hypercapnia • Diuretics
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... in 4 mL) - IV sodium ... therapy (loop diuretics ... mL/min) - Oral sodium ... Acute #Chronic #treatment
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... as no effect on sodium ... Pharmacology #nephrology #conversion ... #loop #thiazide ... #classes
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... 90 minutes) • Sodium ... renal function) - Loop ... diuretic (often ... LouLectures #Hyperkalemia
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Medications - Loop ... abnormalities - Hypercalcemia ... - Hypokalemia ... Hypomagnesemia #Differential ... Classification #Causes
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... overdose) - Sodium ... Furosemide and other loop ... #Medications #differential ... diagnosis #nephrology #Causes
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... - Differential ... Diagnosis Algorithm ... Urine Mg > 10g • Loop ... DiureticsHypercalcemia-PTH
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... #causes #potassium