13 results
Ethacrynic acid - Conversion
Only loop diuretic without a sulfonamide substituent.
Rarely used alternative in patients who have
- Conversion Only ... loop diuretic without ... hypersensitivity reaction ... diuretic. ... #indications #diuretics
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter ... poisoning • Normal acid-base
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... diuretics, and ... thiazide-like diuretics ... diuretic use),
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... CONCENTRATION MEDICATIONS ... • Start with LOOP ... are short acting ... aldosterone states (CHF
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... +2Cl- Symport (Loop ... , Ethacrynic acid ... Tolvaptan) • Treatment ... #Pharmacology #Medications
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter ... and potassium acid
Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the
Acid Base and Blood ... asthma, ↓ Drive, Medications ... D - Diarrhea/diuretics ... Acidosis - non anion ... metabolic acidosis - anion
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... anemia) • G-CSF ... Thyrotoxicosis Medications ... GI losses (NG suction ... • Discontinued diuretic
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... improve GFR - Diuresis ... hypertonic Amp IVP • Diuretics ... (IV loop diuretic ... diuretic (lasix
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
and most diuretics ... limb of Henle's loop ... limb of Henle's loop ... (TAL) - Active ... Segments #Function #Pathophysiology