7 results
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... , nasogastric suction ... anhydrase inhibitors, loop ... syndrome (mimics loop
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... • Start with LOOP ... are short acting ... aldosterone states (CHF ... contraction metabolic alkalosis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... • Metabolic alkalosis ... +2Cl- Symport (Loop ... the Nonspecific Cation ... Tolvaptan) • Treatment
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
Failure (HFrEF) Treatment ... edema then add on loop ... diuretics. ... /ambcarerx #CHF ... Pharmacology #Management #Treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Na delivery): CHF ... (IV loop diuretic ... acetazolamide) - IV loop ... Exchanges K+ for cations ... (10g PO tid) - caution
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... : Supportive + diuresis ... Transfusion #Reactions #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... sepsis), PE, DAH, CHF ... Supportive Care: Diuresis ... diagnosis #management #hematology