18 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... Chlorthalidone POTASSIUM-SPARING ... #Pharmacology #summary ... #table #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
mannitol) 3) Loop ... Diuretics (e.g. ... HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... renal function) - Loop ... diuretic (often ... #Hyperkalemia #management ... #potassium #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... Piretanide Potassium ... #Pharmacology #nephrology ... #conversion #loop
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Summary Trauma ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium ... Loop diuretics for
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... • Start with LOOP ... ) to normalize Potassium ... Early nephrologv ... Fluid #Balance #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Diagnosis and Management ... (IV loop diuretic ... acetazolamide) - IV loop ... #Treatment #potassium ... #nephrology #K
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... irrigation • Management ... +2Cl- Symport (Loop ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Monitor potassium ... Loop diuretics for ... #nephrology
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... therapy (loop diuretics ... Hyperkalemia #Algorithm #Management ... Acute #Chronic #treatment ... #nephrology