11 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
also binds magnesium ... • Mechanism: Sodium-K ... nonspecifically binds ... #pharmacology #table ... #comparison #binders
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... • SPS - Sodium ... #pharmacology #table ... #comparison #nephrology
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Low pill burden. ... Low pill burden ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
in 4 mL) - IV sodium ... binders Chronic ... mL/min) - Oral sodium ... bicarbonate - Consider binders ... Chronic #treatment #nephrology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pump - Digoxin works ... - Hyperkalemia ( ... Because digoxin binds ... , in states of hypokalemia ... (or low potassium
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Inexpensive - Treats hypocalcemia ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na+K ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... differential #diagnosis #table ... #sodium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
reabsorption) Workup ... Elimination (see Table ... acidosis) • Low ... Slow - don’t delay ... Treatment #potassium #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... trial • Minimal K ... Is Dangerous in Hyperkalemia ... decreased renal blood flow ... Normal #Saline #NS #comparison