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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Initial Clinical ... Major Syndromes in Nephrology ... Major #Syndromes #Nephrology ... #Diagnosis #Workup ... #Differential #Table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus Clinical ... Serositis domain: Pleural ... C3 or low C4, Low ... C3 and low C4 ... Erythematosus #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... in >90% - Low ... sle #comparison #table ... #rheumatology #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... 60-80% - Low ... life-threatening • Treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... permeability Diagnosis ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low ... Differential Diagnosis ... Serositis: • Pleural ... , lymphopenia, low
Empyema Necessitans (EN) on Chest Wall Physical Examination

Pulmonary teaching case: you are called to the bedside
he coughed and now ... drain - What’s the diagnosis ... “escapes” the pleura ... Fusobacterium Treatment ... #PhysicalExam #clinical
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
Organizing Pneumonia - Clinical ... Rare: pleural effusions ... , pleural thickening ... other processes Workup ... Organizing Pneumonia Treatment
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
Commonly Used Diagnostic ... negative if on low-gluten ... Reflects response to treatment ... Laboratory #Tests #Diagnosis ... #Workup #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... reabsorption) Workup ... Elimination (see Table ... acidosis) • Low ... #potassium #nephrology