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hematology management anemia reactions classification hemolysis intravascular product agglutinin atlas bandemia cbc coagulation cold comparison dic disseminated encephalopathy extravascular hodgkins
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Causes purpura & ... Malaria, Borrellia (Lyme ... #diagnosis #management ... #hematology #reactions
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... prosthetic valve • Transfusion ... #Diagnosis #causes ... classification #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Causes purpura & ... Malaria, Borrellia (Lyme ... #diagnosis #management ... #hematology #reactions
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... AIHA, Cold AIHA, Transfusion ... - Peripheral Blood ... Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... anemia, Post transfusion ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... of high parity blood ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... hallmark for the disease ... of Peripheral blood ... WBC count and differential ... #Workup #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... younger pts) Differential ... sensitize red blood ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... #management #hematology
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