14 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... the total white blood ... during an allergic reaction ... Colitis and Crohn’s Disease ... #causes #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... Risk factors: Critical ... of high parity blood ... without other cause ... #hematology #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Malaria, Borrellia (Lyme ... (Chagas disease ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... Malaria, Borrellia (Lyme ... (Chagas disease ... #Transfusions #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... DDX - Other causes ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... 40% of patients diagnosed ... plasma cells in blood ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
than 1500 and clinical ... eosinophilia with blood ... eosinophilia Secondary Causes ... Malignancy - Immunologic ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... Malnutrition • Wilson's disease ... deficiency • blood ... Hyophosphatasia #hepatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... Cryofibrinogenemia Clinical ... : • + Clinical ... cryoglobulins • Negative causes ... #rheumatology #hematology