20 results
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... central nervous system ... lupus erythematosus ... #Diagnosis #Rheumatology ... #Diagnosis
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... • Scleroderma (Systemic ... Polymerase Ill • ANCA Vasculitis ... diagnosis #associations
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Labs/Diagnosis: ... lupus erythematosus ... #types #classification ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... the formation of autoantibodies ... permeability Diagnosis ... CNS #neurology #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... inflammation Others: • Lupus ... lupus erythematosus ... #rheumatology # ... classification
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
complexes • Ex: Systemic ... Lupus Erythematosus ... Stevens-Johnson Syndrome ... #Classification ... #Diagnosis #Definitions
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... • Anti-Ro/SSA autoantibodies ... Kikuchi disease • Type-I ... #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... arteritis, Cogan's Syndrome ... Arthritis (RA), Systemic ... lupus erythematosus ... #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
antiphospholipid syndrome ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology