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differential causes hemolytic leukemia management workup chronic classification lymphocytic monoclonal agglutinin bleeding blood cold common cvid diffuse extravascular focal gammopathy
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Algorithm Reactive ... #LAD #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... ) - PAS, TdT Lymphadenopathy ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... #hematology #Markers
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... leukemia in adults • Disorder ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
• Kikuchi Disease ... #LAD #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... Algorithm Hodgkin ... (NHL) ~60% - lymphadenopathy ... pathophysiology #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... Consider sickle cell ... Consider RBC membrane disorder ... #hematology #testing
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) (e.g. lupus, CLL ... lymphoproliferative disorders ... , Copper and lead ... #hematology #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoid malignancy (CLL ... • Symptoms of anemia ... anemia • Cold ... #hemolytic #anemia ... #hematology #diagnosis
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