13 results
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Secondary Causes ... Allergic disorders - Drug ... hypersensitivity - Infection ... Myeloproliferative HES - Lymphocytic ... #diagnosis #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... asthma, allergy, drug ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) ... minimal tumor burden Diagnosis ... Complications: 1) Infection ... #hematology #hemeonc ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • (Peripheral eosinophilia ... • Tumor lysis syndrome ... Leukemia): • Lymphocytes ... #Diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Atypical Lymphocytes ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... transformation to acute leukemia ... #Management #treatment
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
Pseudocellulitis: • Drug ... Sarcoidosis • Eosinophilic ... • Lymphoma • Leukemia ... • Compartment syndrome ... #dermatology #skin
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Antithyroid medications ... - Hepatitis, eosinophilic ... virus (EBV) • Leukemia ... #diagnosis #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... - Drug induced ... cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
: • Infection, ... Electrolyte abnormality, Medication ... /Drug toxicity, ... • Treatment of ... #diagnosis #management