309 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... Splenomegaly 5) Symptoms ... Constitutional symptoms ... hematology #hemeonc #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Findings B & T lymphocyte ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... endocrinology #symptoms ... #signs #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... surface molecules: CD5 ... #Leukemia #diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Large Granular Lymphocytic ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... LargeGranular #Lymphocytic ... hemepath #pathology #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Leukemia (CBC with ... Lymphocytes) ... - Monoclonal Lymphocytes ... #Differential #Diagnosis
Cardiogenic Shock: Pathogenesis, complications and clinical findings

#Cardiogenic #Shock #pathophysiology #cardiology #diagnosis #signs #symptoms
Cardiogenic #Shock #pathophysiology ... #cardiology #diagnosis ... #signs #symptoms
Tuberculous Pleural Effusions - Tests and Biomarkers
Age + fever + red blood cells + ADA -
method Duration of symptoms ... leukocyte count + lymphocytes ... specificity ADA + lymphocyte ... Laboratory #Testing #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Rich, Lymphocyte ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
auto-reactive B and CD ... Sydenham's Chorea Lymphocytes ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... thrombocytosis) CML Symptoms ... Hematology #Oncology #Diagnosis