159 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... transformation) Treatment ... AIHA, PRCA) • Treatment ... hematology #hemeonc #diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Large Granular Lymphocytic ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... LargeGranular #Lymphocytic ... hemepath #pathology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... surface molecules: CD5 ... microglobulin Treatment ... #Leukemia #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Leukemia (CBC with ... Lymphocytes) ... - Monoclonal Lymphocytes ... #Differential #Diagnosis
Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.
Parasitic Cycle ... become adults. 8) Parasitic ... intestine 9) Parasitic ... #diagnosis #pathophysiology ... infectiousdiseases #cdc
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Findings B & T lymphocyte ... hyperplasia Note: B & T lymphocytes ... GravesDisease #pathophysiology ... symptoms #signs #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
) Fungal: • CD4 ... Penicillium marneffei Parasitic ... : • CD4 < 200 ... Primary pulm HTN, Lymphocytic ... HIVAIDS #workup #diagnosis
Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal
Echinococcus #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc ... #parasite
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
Leishmaniasis #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc ... #parasite