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algorithm management causes systemic chronic classification cll disorders generalized lymphocytic myelodysplastic pancytopenia thrombocytosis activation aplastic bandemia cancer cbc erythematosus gap
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... chemotherapy for low-risk disease ... Lauren Banaszak, MD ... #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #primary #secondary ... #generalized #dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... cytopenias (usually anemia ... transformation to acute leukemia ... #MDS #Diagnosis ... #hematology #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Hyperthyroidism CBC ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... bone marrow and secondary ... #Hematology #Oncology ... #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Metastatic Disease ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Metastatic Disease ... #Hematology
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