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diagnosis hematology differential management oncology algorithm comparison diseases fingernails hepatology leukemia lupus sle systemic table abnormal aorticregurgitation approach arthritis ascites
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Congestive • Cirrhosis ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cells can indicate disease ... Leukemia #diagnosis #workup ... #oncology #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology: • T lymphocyte ... intralobular bile ducts causes ... cholestasis → Cirrhosis ... cholangitis #diagnosis #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... patients if the cause ... #Workup #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
the population Disease ... decades of life Causes ... fever, fatigue, Nausea ... infiltration (lymphocytes ... Urticaria #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... -> AML: Blast crises ... CLL (Chronic Lymphocytic ... #Leukemia #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulopathy, cirrhosis ... Chain deposition disease ... #differential #hematology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... (e.g. cirrhosis ... of underlying disease ... Jcortesizaguirr #Ascites #workup
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Colitis and Crohn’s Disease ... Chickenpox Other Causes ... Irradiation • Cirrhosis ... Differential #Diagnosis #causes ... #hematology #basophils
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... Positive in 60-80% of cases ... Evolution: Chronic disease ... Management #Summary #rheumatology
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