14 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Poliomyelitis, Guillain-Barre ... Eaton Syndrome, Myasthenia ... #Causes #differential ... #diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Ocular- 50%: Ptosis ... crises”. ... Diagnosis - ... AchR antibodies: first ... Crises - Severe
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Clinical Features ... Diagnosis: • ... axonal form • MRI ... #Syndrome #diagnosis
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
: • Based on clinical ... More likely to cause ... Symptomatic treatment Of ocular ... glucocorticoids - can cause ... - Improves clinical
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... - Differential Diagnosis ... Rhabdomyolysis, Critical ... NMJ disorder (Myasthenia ... #causes #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... demyelinating or axonal • MRI ... - Spinal MRI may ... #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Weakness: - Weakness ... bouts of HTN Diagnostic ... • Infectious causes ... #management #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
- Emergency Causes ... cord • Guillain-Barre ... lower extremity weakness ... Imaging studies: • MRI ... #causes #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... involvement: Intractable nausea ... Sjögren syndrome, Myasthenia ... Manifestations #diagnosis
Retinoblastoma - MRI
 • Most common intra-ocular neoplasm in children.
 • Clinical Presentation: leukocoria (loss of
Retinoblastoma - MRI ... Most common intra-ocular ... • Clinical Presentation ... the first 4 years ... tumours (60-70%) are caused