27 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Nephritic #Nephrotic ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... sensitive) • AKI ... sterile pyuria, WBC casts ... proteinuria, granular casts ... #Interstitial #Nephritis
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential ... blood cells on urine ... RBCs and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... sodium retention, Urine ... • NSAlDs • AKI ... /CKD • Nephrotic ... Oncotic Pressure • Nephrotic
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... polyangiitis /microscopic ... Acute Interstitial Nephritis ... #KidneyInjury #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
, urine microscopy ... osmolarity If cause ... • Interstitial nephritis ... #Diagnosis #nephrology ... #causes
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Urinary obstruction, Nephrotoxic ... cases are caused ... IMPROVEMENT If the urine ... Assess UA w/ microscopy ... for WBCs, RBCs, casts