19 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... Proteinuria often ... but in severe cases ... Massive proteinuria ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria and/or proteinuria ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... - Differential ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... #Nephrology #Differential
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Differential #
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts ... range) proteinuria
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... key #diagnosis #nephrology ... #casts
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... eosinophiluria, microscopic ... , mild tubular proteinuria ... , granular casts ... AIN #Algorithm #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... hematuria: - RBC casts ... - Proteinuria ... #Hematuria #Differential ... #urology #nephrology
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
develops new: • Proteinuria ... urine sediment ... dysmorphic RBCs, RBC casts ... , WBC casts) especially ... algorithm #sle #nephrology