104 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al ... Normotensive: • UCl ... Post-hypercapnia • UCl ... #Hypokalemia #Differential
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... cotransporter, K channel, Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... Nephrology #Diagnosis #Differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... Microcytic (MCV ... Thalassemia • ACD ... Non-hemolytic: ACD ... #Algorithm #Differential
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Myeloid Leukemia (AML ... Myeloid Leukemia (CML ... drugs • ACE ... Hyperuricemia #Differential
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Syndrome - Causes and Treatment ... transformation (CML ... hyperleukocytosis (AML ... Syndrome #Causes #Differential ... #Diagnosis #Treatment
Urine Anion Gap in NAGMA
NA + K - Cl = surrogate for Urine NH4+
NH4+ is excreted
NAGMA NA + K - Cl ... excreted with Cl ... is intact: - All ... NAGMA #diagnosis #differential
Lidocaine HCl - sodium channel blocker. Local anesthetic and class 1B antiarrhythmic. Originally developed in 1943
Lidocaine HCl - ... #Pharmacology #Lidocaine
Medications Used in Hypertensive Emergencies
Vasodilators: Hydralazine, Nitroglycerin, Sodium nitroprusside 
Calcium Channel Blockers: Clevidipine, Nicardipine
ß-Blockers: Esmolol, Labetalol,
Labetalol, Metoprolol ACE ... Medications #Management #Treatment ... #Pharmacology #
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
+, Mg2+, Ca2+, Cl ... electrolytes #effects #pharmacology