277 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
, others (RNP, aPL ... Anti-cardiolipin (aCl ... Anti-centromere, Scl ... #Rheumatology #diagnosis
Knee Examination
Right Knee - Examination maneuvers include the Lachman (ACL), anterior drawer (ACL), Lateral pivot shift,
include the Lachman (ACL ... anterior drawer (ACL ... #Diagnosis #Sports
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #differential #diagnosis ... pathophysiology #pharmacology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... cotransporter, K channel, Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... Kidney #Nephrology #Diagnosis
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential Diagnosis ... Hypertensive: • High Al ... Normotensive: • UCl ... Post-hypercapnia • UCl ... #Differential #Diagnosis
Lidocaine HCl - sodium channel blocker. Local anesthetic and class 1B antiarrhythmic. Originally developed in 1943
Lidocaine HCl - ... #Pharmacology #Lidocaine
Guide to systemic mastocytosis

Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
Criteria for diagnosis ... infiltrates of MC ... Minor: • >25% of all ... MCs are atypical ... pathology #algorithm #diagnosis
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Dobutamine 2-20 mcg ... Isoproterenol 2-10 mcg ... Epinephrine 0-20 mcg ... Properties #Table #Pharmacology ... #Effect #Management
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential Diagnosis ... Framework by MCV ... Thalassemia • ACD ... Non-hemolytic: ACD ... #Differential #Diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... involvement CML ... ↓ LAP Score • CML ... lymphadenopathy CML ... Hematology #Oncology #Diagnosis