13 results
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Thalassemia • ACD ... Non-hemolytic: ACD ... #Differential # ... Diagnosis #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... , Auer rod • Lymphoid ... Pelger-Huet, Macrocytic anemia ... CD23, o CML ... Blood #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... - infiltrates (anemia ... and secondary lymphoid ... of large cell lymphoma ... #Leukemia #Hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antibody Testing - Nuclear ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involvement Differential ... Malignancies (eg CML ... , ALL) • Solid ... oncology #diagnosis #differential ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... classical HL (MCHL ... Immunohistochemical studies (to differentiate
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... changes), high MCV ... anemia (vegan, ... not required in all ... Causes #Workup #hematology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antibody Testing - Nuclear ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... #Patterns #differential ... #diagnosis #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... Evans • ITP • Cl-NH ... (-) hemolytic anemia ... #Monoclonal #Differential
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... DIAGNOSTIC CRITERIA FOR ICL ... Unc119) • Heme (lymphoma ... #Lymphopenia #ICL ... #Differential #